Phytochemistry and Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Bioactive Components of Methanolic Root-Bark Extract of Boswellia dalzielii (Burseraceae)
9.38$
Year : 2022,
Volume & Issue : BPAS-Chemistry 41C(1), JAN-JUN 2022
Page No. : 9-21,
Article Type : Original Aticle
Article DOI : 10.5958/2320-320X.2022.00002.4 (Received on 15.02.2022 Revised on 24.04.2022 Accepted on 13.05.2022)
Description
Description
Mamza UT*1, Rabiu M2, Khan S3, Shah M4, Arshad M5, Yakubu J6, Dawa SI7, Sule I8 and Khan IZ9
Author’s Affiliation : 1,2,6,8,9Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria 3Suny Downstate Health Sciences University, Department of Pediatrics Children’s Hospital New York, USA. 4Parsons 10625 Rd, Johns Creek, GA 30097 Atlanta, USA. 5Study Hall, Vipul Khand, Gomti, Nagar, Lucknow, Uttar Pradesh 226010, India 7Department of Chemistry, Borno State University, Maiduguri, Borno State, Nigeria
Corresponding Author : Dr. U.T. Mamza, Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria,
E-Mail:-utmamza@unimaid.edu.ng, drutmamza_2587@yahoo.com
Abstract
This study was conducted to identify phytochemical constituents present in the methanolic root-bark extract of B. dalzielii using GC-MS analysis and conventional phytochemical evaluation. The studies revealed the presence of alkaloids, flavonoids, saponins, cardiac glycosides, terpenoids and carbohydrates. A total of forty three compounds composed of eighteen major components were identified thus; oxetane-2,3,4-trimethyl (3.45%), Bicyclo[4.1.0] heptan-3-one-7,7-dimethyl-4-methylene(IR) [2.69%], 2-methyl-2-(-2-oxopropyl) furan (3.20%), Cyclohexane, 2-(dimethylhydrazono)-3-[4-hexenyl]-1-acinitro,(E,) [2.63%], 3,8-Dihydroxy-3,4-dihydronaphthalen-1(2H)one (4.43%), 2-Tetradocanol (4.89%), 3-methyl-2-(2-oxopropyl)furan (3.46%), (2H)-Naphthalenenone, 6-(1,1-dimethyl ethyl) octahydro-2,8a-dimethyl (3.80%), Pentadecanoic acid (6.18%), undecanoic acid (3.68%), Phthalic acid (4.14%), 1-Allyl-cyclohexane-1,2-diol (3.95%), 1,5,9-cyclotetradecatriene, 1,5,9-trimethyl-12-(1-methyl ethyl) [4.58%], 9,12-octadecadienoic acid (Z,Z)-methyl ester (4.75%). 9-octadecenoic acid, methyl ester[E] (4.36%), Tetradecanoic acid-methyl ester(S) [3.90%], (2S,4R)-p-mentha-[1(7),8]-diene-2-hydroperoxide (2.62%) and 1-Naphthalenepropanol, α-ethyldecahydro-8a-(hydroxymethyl)-α, 5-dimethyl-2-methylene (2.93%). Most of the identified compounds have been reported to possess various biological activities such as antimicrobial, anti-inflammatory, antimalarial, antidiabetics, anti-asthmatic, anti-histamine, antitubercular, anti-diarrhoeal among others. The studies thus concluded that B. dalzielii root-bark possesses potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance. The presence of these bioactive compounds justifies the use of this plant in ethnomedicine.
How to cite this article: Mamza UT, Rabiu M, Khan S, Shah M, Arshad M, Yakubu J, Dawa SI, Sule I. and Khan IZ. (2022). Phytochemistry and Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Bioactive Components of Methanolic Root-Bark Extract of Boswellia dalzielii (Burseraceae).Bulletin of Pure and Applied Sciences-Chemistry, 41C (1), 9-21.
Keywords
Phytochemistry, GC-MS Analysis, Bioactive compounds, Root-bark extract, Boswellia dalzielii
