The Number of General Leukocytes in the Blood of Karakul Sheep Farmed in Different Climate and Nutritional Conditions Depends on the Seasons of the Immune System

The article describes the dynamics of changes in the blood of leukocytes and the immune system depending on the seasons in the blood of karakul sheep fed in different climates and feeding conditions. The amount of many biochemical components in the blood of Karakul sheep varies depending on the seasons, feeding conditions and physiological conditions. This condition is especially evident in the changes in metabolism in winter and spring, as these conditions occur as a result of poor nutrition and lack of nutrients. Leukocyte formula or the percentage of leukocytes in the blood to each other called a leukogram. Determining the percentage of leukocytes in the blood is important in making a diagnosis and predicting the consequences that can be observed.   Determination of the leukocyte formula in Karakul sheep allows a perfect calculation of the amount of basophils, eosinophils, neutrophils, lymphocytes and monocytes among the 100 leukocytes listed in the sample. Lymphocytes play a key role in the   body's special protective reactions,  ie the formation of cellular and humoral immunity.   Keywords: Karakul Sheep, Immune System, Leukocytes, Leukoformula, Climatic Factors, Seasons, Pastures.